I have Sansha's Scout Outpost in my home region. If I play Scordite, does Sansha's Scout Outpost go back in my hand or can I sacrifice it?

It goes to your hand. Sansha's Scout Outpost's pending ability happens when you play a location into its region, but Scordite's pending ability happens when it comes into play. When you pay Scordite's price and place it on the pile, that is when Sansha's Scout Outpost's pending ability goes on the pile and therefore returns it to your hand before Scordite enters play.